Drug interactions
Saxagliptin + Tecovirimat
Severity: Minor
Saxagliptin and Tecovirimat: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Tecovirimat is a weak CYP3A4 inducer and may slightly reduce saxagliptin exposure. It is given for a short course, so clinically meaningful loss of glucose control is unlikely.
What this interaction means in plain words
Saxagliptin and Tecovirimat have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Saxagliptin belongs to Endocrine; Tecovirimat belongs to Miscellaneous.
Why it happens
Weak induction of CYP3A4 by tecovirimat increases saxagliptin clearance.
What to do
No dose adjustment needed; check glucose if control appears to worsen during the course.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Saxagliptin
- Albiglutide + Saxagliptin Moderate
- Amlodipine-benazepril + Saxagliptin Moderate
- Aripiprazole + Saxagliptin Moderate
- Asenapine + Saxagliptin Moderate
- Atazanavir + Saxagliptin Moderate
- Benazepril + Saxagliptin Moderate
Other interactions of Tecovirimat
- Bosentan + Tecovirimat Moderate
- Cyclosporin + Tecovirimat Moderate
- Darunavir + Tecovirimat Moderate
- Ethinyl estradiol-drospirenone + Tecovirimat Moderate
- Ethinyl estradiol-levonorgestrel + Tecovirimat Moderate
- Glimepiride-pioglitazone + Tecovirimat Moderate
Frequently asked questions
Can I take Saxagliptin with Tecovirimat?
MediHelp rates the interaction as minor. Saxagliptin and Tecovirimat have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Tecovirimat is a weak CYP3A4 inducer and may slightly reduce saxagliptin exposure. It is given for a short course, so clinically meaningful loss of glucose control is unlikely.
How serious is the interaction between Saxagliptin and Tecovirimat?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose adjustment needed; check glucose if control appears to worsen during the course.
What other medicines interact with Saxagliptin?
MediHelp also lists interactions of Saxagliptin with, for example, Albiglutide, Amlodipine-benazepril, Aripiprazole. The full list is on the Saxagliptin page.
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