Drug interactions
Scopolamine + Umeclidinium
Severity: Moderate
Scopolamine and Umeclidinium: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Scopolamine is a centrally active antimuscarinic, so using it with umeclidinium may increase anticholinergic effects such as dry mouth, drowsiness, confusion, urinary retention and blurred vision. Older patients are especially vulnerable.
What this interaction means in plain words
Scopolamine and Umeclidinium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Scopolamine belongs to Respiratory; Umeclidinium belongs to Respiratory.
Why it happens
Additive antimuscarinic pharmacodynamic effects.
What to do
Avoid combining where possible, and monitor for confusion, urinary retention and eye symptoms, especially in older adults.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Umeclidinium
- Tiotropium + Umeclidinium Major
- Aclidinium + Umeclidinium Moderate
- Atropine iv / + Umeclidinium Moderate
- Atropine + Umeclidinium Moderate
- Belladonna alkaloids + Umeclidinium Moderate
- Bethanechol + Umeclidinium Moderate
Other interactions of Scopolamine
Frequently asked questions
Can I take Scopolamine with Umeclidinium?
MediHelp rates the interaction as moderate. Scopolamine and Umeclidinium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Scopolamine is a centrally active antimuscarinic, so using it with umeclidinium may increase anticholinergic effects such as dry mouth, drowsiness, confusion, urinary retention and blurred vision. Older patients are especially vulnerable.
How serious is the interaction between Scopolamine and Umeclidinium?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid combining where possible, and monitor for confusion, urinary retention and eye symptoms, especially in older adults.
What other medicines interact with Umeclidinium?
MediHelp also lists interactions of Umeclidinium with, for example, Tiotropium, Aclidinium, Atropine iv /. The full list is on the Umeclidinium page.
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