Drug interactions
Solriamfetol + Terbutaline
Severity: Moderate
Solriamfetol and Terbutaline: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Solriamfetol raises blood pressure and heart rate, and terbutaline has additional sympathomimetic cardiovascular effects. Combined use may increase the risk of hypertension, tachycardia and palpitations.
What this interaction means in plain words
Solriamfetol and Terbutaline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Solriamfetol belongs to Central Nervous System; Terbutaline belongs to Respiratory.
Why it happens
Additive sympathomimetic effects: dopamine and norepinephrine reuptake inhibition (solriamfetol) plus beta-2 agonism (terbutaline).
What to do
Monitor blood pressure and heart rate, particularly after initiation or dose increases. Control existing hypertension before combining.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Terbutaline
Other interactions of Solriamfetol
- Isocarboxazid + Solriamfetol Contraindicated
- Linezolid + Solriamfetol Contraindicated
- Phenelzine + Solriamfetol Contraindicated
- Procarbazine + Solriamfetol Contraindicated
- Rasagiline + Solriamfetol Contraindicated
- Safinamide + Solriamfetol Contraindicated
Frequently asked questions
Can I take Solriamfetol with Terbutaline?
MediHelp rates the interaction as moderate. Solriamfetol and Terbutaline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Solriamfetol raises blood pressure and heart rate, and terbutaline has additional sympathomimetic cardiovascular effects. Combined use may increase the risk of hypertension, tachycardia and palpitations.
How serious is the interaction between Solriamfetol and Terbutaline?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and heart rate, particularly after initiation or dose increases. Control existing hypertension before combining.
What other medicines interact with Terbutaline?
MediHelp also lists interactions of Terbutaline with, for example, Carvedilol, Droperidol, Fexinidazole. The full list is on the Terbutaline page.
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