Drug interactions
Teriflunomide + Trastuzumab
Severity: Moderate
Teriflunomide and Trastuzumab: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Teriflunomide is immunosuppressive and can cause neutropenia, and trastuzumab increases neutropenia when given with myelosuppressive therapy. Combined use may raise the risk of infection.
What this interaction means in plain words
Teriflunomide and Trastuzumab can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Teriflunomide belongs to Central Nervous System; Trastuzumab belongs to Oncology.
Why it happens
Additive immunosuppressive and hematologic effects.
What to do
Monitor blood counts and signs of infection during combined therapy.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Teriflunomide
Other interactions of Trastuzumab
Frequently asked questions
Can I take Teriflunomide with Trastuzumab?
MediHelp rates the interaction as moderate. Teriflunomide and Trastuzumab can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Teriflunomide is immunosuppressive and can cause neutropenia, and trastuzumab increases neutropenia when given with myelosuppressive therapy. Combined use may raise the risk of infection.
How serious is the interaction between Teriflunomide and Trastuzumab?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood counts and signs of infection during combined therapy.
What other medicines interact with Teriflunomide?
MediHelp also lists interactions of Teriflunomide with, for example, Ifosfamide, Lomustine, Amiodarone. The full list is on the Teriflunomide page.
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