Drug interactions
Tiotropium-olodaterol + Vardenafil
Severity: Minor
Tiotropium-olodaterol and Vardenafil: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Vardenafil can cause a small QT prolongation, and olodaterol can add tachycardia and hypokalemia. The combination may modestly increase arrhythmia risk in predisposed patients.
What this interaction means in plain words
Tiotropium-olodaterol and Vardenafil have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Tiotropium-olodaterol belongs to Respiratory; Vardenafil belongs to Genitourinary.
Why it happens
Additive effects on cardiac repolarization and heart rate.
What to do
Monitor for palpitations and arrhythmia in patients with cardiac disease or other QT risk factors.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Tiotropium-olodaterol
Other interactions of Vardenafil
- Amyl nitrite + Vardenafil Contraindicated
- Glyceryl trinitrate pr + Vardenafil Contraindicated
- Isosorbide dinitrate + Vardenafil Contraindicated
- Isosorbide mononitrate + Vardenafil Contraindicated
- Nicorandil + Vardenafil Contraindicated
- Nitroglycerin po + Vardenafil Contraindicated
Frequently asked questions
Can I take Tiotropium-olodaterol with Vardenafil?
MediHelp rates the interaction as minor. Tiotropium-olodaterol and Vardenafil have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Vardenafil can cause a small QT prolongation, and olodaterol can add tachycardia and hypokalemia. The combination may modestly increase arrhythmia risk in predisposed patients.
How serious is the interaction between Tiotropium-olodaterol and Vardenafil?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for palpitations and arrhythmia in patients with cardiac disease or other QT risk factors.
What other medicines interact with Tiotropium-olodaterol?
MediHelp also lists interactions of Tiotropium-olodaterol with, for example, Amisulpride, Arformoterol, Arsenic trioxide. The full list is on the Tiotropium-olodaterol page.
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