Drug interactions
Vitamin e + Vortioxetine
Severity: Minor
Vitamin e and Vortioxetine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
High-dose vitamin E has mild antiplatelet and anticoagulant-like effects, and vortioxetine may impair platelet function. Combined use could slightly increase bleeding tendency, though evidence is limited.
What this interaction means in plain words
Vitamin e and Vortioxetine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Vitamin e belongs to Gastrointestinal Tract; Vortioxetine belongs to Central Nervous System.
Why it happens
Possible additive effect on platelet function.
What to do
No routine change is needed; avoid high-dose vitamin E supplements in patients also taking anticoagulants or antiplatelets, and monitor for bleeding.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Vortioxetine
- Isocarboxazid + Vortioxetine Contraindicated
- Linezolid + Vortioxetine Contraindicated
- Methylene blue + Vortioxetine Contraindicated
- Phenelzine + Vortioxetine Contraindicated
- Rasagiline + Vortioxetine Contraindicated
- Selegiline transdermal + Vortioxetine Contraindicated
Other interactions of Vitamin e
- Betrixaban + Vitamin e Moderate
- Phenindione + Vitamin e Moderate
- Selumetinib + Vitamin e Moderate
- Vitamin e + Warfarin Moderate
- Alfalfa + Vitamin e Minor
- Antithrombin alfa + Vitamin e Minor
Frequently asked questions
Can I take Vitamin e with Vortioxetine?
MediHelp rates the interaction as minor. Vitamin e and Vortioxetine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. High-dose vitamin E has mild antiplatelet and anticoagulant-like effects, and vortioxetine may impair platelet function. Combined use could slightly increase bleeding tendency, though evidence is limited.
How serious is the interaction between Vitamin e and Vortioxetine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine change is needed; avoid high-dose vitamin E supplements in patients also taking anticoagulants or antiplatelets, and monitor for bleeding.
What other medicines interact with Vortioxetine?
MediHelp also lists interactions of Vortioxetine with, for example, Isocarboxazid, Linezolid, Methylene blue. The full list is on the Vortioxetine page.
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