Interactions médicamenteuses
Deferasirox + Prasugrel
Gravité: Majeure
Deferasirox and Prasugrel: major interaction.
Dernière mise à jour
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Résumé
Deferasirox can cause GI ulceration and hemorrhage, and prasugrel potently inhibits platelet aggregation. Together they markedly raise the risk of serious GI bleeding.
Ce que signifie cette interaction, en termes simples
Deferasirox and Prasugrel can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Deferasirox belongs to Miscellaneous; Prasugrel belongs to Cardiovascular.
Pourquoi elle survient
Additive bleeding risk from deferasirox mucosal injury and irreversible P2Y12 platelet inhibition.
Conduite à tenir
Monitor for GI bleeding and hemoglobin, consider gastroprotection with a proton pump inhibitor, and reassess the need for both drugs in patients with bleeding risk.
Questions à poser à votre pharmacien
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Autres interactions de Deferasirox
- Acetylsalicylic acid + Deferasirox Majeure
- Alosetron + Deferasirox Majeure
- Aluminum hydroxide + Deferasirox Majeure
- Amikacin + Deferasirox Majeure
- Argatroban + Deferasirox Majeure
- Aspirin / citric acid / sodium bicarbonate + Deferasirox Majeure
Autres interactions de Prasugrel
- Acetylsalicylic acid + Prasugrel Majeure
- Apixaban + Prasugrel Majeure
- Argatroban + Prasugrel Majeure
- Cangrelor + Prasugrel Majeure
- Celecoxib + Prasugrel Majeure
- Dabigatran etexilate + Prasugrel Majeure
Questions fréquentes
Can I take Deferasirox with Prasugrel?
MediHelp rates the interaction as major. Deferasirox and Prasugrel can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Deferasirox can cause GI ulceration and hemorrhage, and prasugrel potently inhibits platelet aggregation. Together they markedly raise the risk of serious GI bleeding.
How serious is the interaction between Deferasirox and Prasugrel?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for GI bleeding and hemoglobin, consider gastroprotection with a proton pump inhibitor, and reassess the need for both drugs in patients with bleeding risk.
What other medicines interact with Deferasirox?
MediHelp also lists interactions of Deferasirox with, for example, Acetylsalicylic acid, Alosetron, Aluminum hydroxide. The full list is on the Deferasirox page.
Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp
Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
