Interazioni tra farmaci
Amlodipine-atorvastatin + Calcium gluconate
Gravità: Moderata
Amlodipine-atorvastatin and Calcium gluconate: moderate interaction.
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Sintesi
Intravenous calcium gluconate can reverse the effects of calcium channel blockers, so a bolus may temporarily reduce the blood pressure lowering effect of amlodipine. Oral supplementation has little effect.
Cosa significa questa interazione in parole semplici
Amlodipine-atorvastatin and Calcium gluconate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Amlodipine-atorvastatin belongs to Cardiovascular; Calcium gluconate belongs to Gastrointestinal Tract.
Perché avviene
Raised extracellular calcium competitively overcomes calcium channel blockade by amlodipine.
Cosa fare
Monitor blood pressure when giving intravenous calcium to patients on amlodipine; no change is needed for ordinary oral supplements.
Cosa chiedere al farmacista
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Altre interazioni di Amlodipine-atorvastatin
Altre interazioni di Calcium gluconate
- Calcium gluconate + Ceftriaxone Controindicata
- Calcium gluconate + Digoxin Maggiore
- Alendronate + Calcium gluconate Moderata
- Amlodipine-hydrochlorothiazide-valsartan + Calcium gluconate Moderata
- Amlodipine-olmesartan-hydrochlorothiazide + Calcium gluconate Moderata
- Amlodipine-perindopril + Calcium gluconate Moderata
Domande frequenti
Can I take Amlodipine-atorvastatin with Calcium gluconate?
MediHelp rates the interaction as moderate. Amlodipine-atorvastatin and Calcium gluconate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Intravenous calcium gluconate can reverse the effects of calcium channel blockers, so a bolus may temporarily reduce the blood pressure lowering effect of amlodipine. Oral supplementation has little effect.
How serious is the interaction between Amlodipine-atorvastatin and Calcium gluconate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure when giving intravenous calcium to patients on amlodipine; no change is needed for ordinary oral supplements.
What other medicines interact with Amlodipine-atorvastatin?
MediHelp also lists interactions of Amlodipine-atorvastatin with, for example, Amifostine, Apalutamide, Atazanavir. The full list is on the Amlodipine-atorvastatin page.
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