Interazioni tra farmaci
Benazepril + Isosorbide dinitrate
Gravità: Moderata
Benazepril and Isosorbide dinitrate: moderate interaction.
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Sintesi
Nitrates cause venous and arterial dilation, and combining them with an ACE inhibitor can lower blood pressure further. This is often used intentionally but may cause symptomatic hypotension, especially at initiation.
Cosa significa questa interazione in parole semplici
Benazepril and Isosorbide dinitrate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Benazepril belongs to Cardiovascular; Isosorbide dinitrate belongs to Cardiovascular.
Perché avviene
Additive vasodilatory and hypotensive effects.
Cosa fare
Monitor blood pressure and orthostatic symptoms when starting or increasing either drug. Adjust doses if symptomatic hypotension occurs.
Cosa chiedere al farmacista
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Altre interazioni di Benazepril
- Aliskiren + Benazepril Controindicata
- Benazepril + Sacubitril / valsartan Controindicata
- Benazepril + Sacubitril-valsartan Controindicata
- Amifostine + Benazepril Maggiore
- Amiloride + Benazepril Maggiore
- Amlodipine-hydrochlorothiazide-valsartan + Benazepril Maggiore
Altre interazioni di Isosorbide dinitrate
- Avanafil + Isosorbide dinitrate Controindicata
- Isosorbide dinitrate + Riociguat Controindicata
- Isosorbide dinitrate + Sildenafil Controindicata
- Isosorbide dinitrate + Tadalafil Controindicata
- Isosorbide dinitrate + Vardenafil Controindicata
- Ergotamine + Isosorbide dinitrate Maggiore
Domande frequenti
Can I take Benazepril with Isosorbide dinitrate?
MediHelp rates the interaction as moderate. Benazepril and Isosorbide dinitrate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Nitrates cause venous and arterial dilation, and combining them with an ACE inhibitor can lower blood pressure further. This is often used intentionally but may cause symptomatic hypotension, especially at initiation.
How serious is the interaction between Benazepril and Isosorbide dinitrate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and orthostatic symptoms when starting or increasing either drug. Adjust doses if symptomatic hypotension occurs.
What other medicines interact with Benazepril?
MediHelp also lists interactions of Benazepril with, for example, Aliskiren, Sacubitril / valsartan, Sacubitril-valsartan. The full list is on the Benazepril page.
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