相互作用
Cabotegravir + Magnesium hydroxide
重症度: 中等度
Cabotegravir and Magnesium hydroxide: moderate interaction.
最終更新日
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概要
Magnesium antacids chelate oral cabotegravir in the gut and may lower its plasma levels, risking reduced antiviral effect. This applies to the oral formulation only.
この相互作用をわかりやすく説明すると
Cabotegravir and Magnesium hydroxide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Cabotegravir belongs to Anti Virals; Magnesium hydroxide belongs to Gastrointestinal Tract.
なぜ起こるのか
Magnesium cations chelate cabotegravir in the GI tract, reducing absorption.
対処法
Give the antacid at least 2 hours before or 4 hours after oral cabotegravir.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、CabotegravirとMagnesium hydroxideの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Magnesium hydroxideのその他の相互作用
Cabotegravirのその他の相互作用
よくある質問
Can I take Cabotegravir with Magnesium hydroxide?
MediHelp rates the interaction as moderate. Cabotegravir and Magnesium hydroxide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Magnesium antacids chelate oral cabotegravir in the gut and may lower its plasma levels, risking reduced antiviral effect. This applies to the oral formulation only.
How serious is the interaction between Cabotegravir and Magnesium hydroxide?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give the antacid at least 2 hours before or 4 hours after oral cabotegravir.
What other medicines interact with Magnesium hydroxide?
MediHelp also lists interactions of Magnesium hydroxide with, for example, Ciprofloxacin, Dolutegravir, Gemifloxacin. The full list is on the Magnesium hydroxide page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
