相互作用
Aripiprazole + Guanfacine
重症度: 中等度
Aripiprazole and Guanfacine: moderate interaction.
最終更新日
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概要
Both drugs can lower blood pressure, so the combination can cause dizziness, orthostatic hypotension and syncope. Additive sedation is also possible.
この相互作用をわかりやすく説明すると
Aripiprazole and Guanfacine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Aripiprazole belongs to Central Nervous System; Guanfacine belongs to Cardiovascular.
なぜ起こるのか
Additive hypotensive and sedative effects from central alpha-2 agonism and alpha-1 blockade.
対処法
Monitor blood pressure and heart rate, including standing readings, especially at start or dose changes. Advise rising slowly and adjust doses if symptomatic.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、AripiprazoleとGuanfacineの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Aripiprazoleのその他の相互作用
Guanfacineのその他の相互作用
よくある質問
Can I take Aripiprazole with Guanfacine?
MediHelp rates the interaction as moderate. Aripiprazole and Guanfacine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs can lower blood pressure, so the combination can cause dizziness, orthostatic hypotension and syncope. Additive sedation is also possible.
How serious is the interaction between Aripiprazole and Guanfacine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and heart rate, including standing readings, especially at start or dose changes. Advise rising slowly and adjust doses if symptomatic.
What other medicines interact with Aripiprazole?
MediHelp also lists interactions of Aripiprazole with, for example, Pimozide, Thioridazine, Amisulpride. The full list is on the Aripiprazole page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
