相互作用
Arsenic trioxide + Budesonide-formoterol
重症度: 重大
Arsenic trioxide and Budesonide-formoterol: major interaction.
最終更新日
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概要
Arsenic trioxide markedly prolongs QT and can cause torsades de pointes. Formoterol can add to QT effects and lower potassium, increasing arrhythmia risk.
この相互作用をわかりやすく説明すると
Arsenic trioxide and Budesonide-formoterol can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Arsenic trioxide belongs to Oncology; Budesonide-formoterol belongs to Respiratory.
なぜ起こるのか
Additive QT prolongation, with beta-agonist-induced hypokalemia.
対処法
Avoid when possible; if needed, monitor ECG and keep potassium and magnesium within normal range. Use a non-beta-agonist alternative where feasible.
薬剤師に尋ねること
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、Arsenic trioxideとBudesonide-formoterolの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Budesonide-formoterolのその他の相互作用
Arsenic trioxideのその他の相互作用
よくある質問
Can I take Arsenic trioxide with Budesonide-formoterol?
MediHelp rates the interaction as major. Arsenic trioxide and Budesonide-formoterol can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Arsenic trioxide markedly prolongs QT and can cause torsades de pointes. Formoterol can add to QT effects and lower potassium, increasing arrhythmia risk.
How serious is the interaction between Arsenic trioxide and Budesonide-formoterol?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid when possible; if needed, monitor ECG and keep potassium and magnesium within normal range. Use a non-beta-agonist alternative where feasible.
What other medicines interact with Budesonide-formoterol?
MediHelp also lists interactions of Budesonide-formoterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Budesonide-formoterol page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
