相互作用
Atropine + Bethanechol
重症度: 中等度
Atropine and Bethanechol: moderate interaction.
最終更新日
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概要
Atropine is a competitive muscarinic antagonist and directly opposes the muscarinic agonist effects of bethanechol on the bladder, gut and other organs. Bethanechol may therefore lose its efficacy, and atropine can be used to reverse bethanechol toxicity.
この相互作用をわかりやすく説明すると
Atropine and Bethanechol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Atropine belongs to Miscellaneous; Bethanechol belongs to Gastrointestinal Tract.
なぜ起こるのか
Pharmacodynamic antagonism at muscarinic receptors.
対処法
Avoid routine co-administration because therapeutic effect is lost; if bethanechol overdose or cholinergic toxicity occurs, atropine is the appropriate antidote.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、AtropineとBethanecholの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Bethanecholのその他の相互作用
Atropineのその他の相互作用
よくある質問
Can I take Atropine with Bethanechol?
MediHelp rates the interaction as moderate. Atropine and Bethanechol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Atropine is a competitive muscarinic antagonist and directly opposes the muscarinic agonist effects of bethanechol on the bladder, gut and other organs. Bethanechol may therefore lose its efficacy, and atropine can be used to reverse bethanechol toxicity.
How serious is the interaction between Atropine and Bethanechol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid routine co-administration because therapeutic effect is lost; if bethanechol overdose or cholinergic toxicity occurs, atropine is the appropriate antidote.
What other medicines interact with Bethanechol?
MediHelp also lists interactions of Bethanechol with, for example, Darifenacin, Fesoterodine, Oxybutynin. The full list is on the Bethanechol page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
