相互作用
Azithromycin + Pasireotide
重症度: 重大
Azithromycin and Pasireotide: major interaction.
最終更新日
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概要
Both drugs can prolong the QT interval, and pasireotide also causes bradycardia, increasing the risk of torsades de pointes.
この相互作用をわかりやすく説明すると
Azithromycin and Pasireotide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Azithromycin belongs to Anti Bacterial; Pasireotide belongs to Endocrine.
なぜ起こるのか
Additive QT prolongation, with pasireotide-related bradycardia as a contributing factor.
対処法
Monitor ECG and correct potassium and magnesium before and during therapy. Consider an alternative to azithromycin when feasible.
薬剤師に尋ねること
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、AzithromycinとPasireotideの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Azithromycinのその他の相互作用
Pasireotideのその他の相互作用
よくある質問
Can I take Azithromycin with Pasireotide?
MediHelp rates the interaction as major. Azithromycin and Pasireotide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Both drugs can prolong the QT interval, and pasireotide also causes bradycardia, increasing the risk of torsades de pointes.
How serious is the interaction between Azithromycin and Pasireotide?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ECG and correct potassium and magnesium before and during therapy. Consider an alternative to azithromycin when feasible.
What other medicines interact with Azithromycin?
MediHelp also lists interactions of Azithromycin with, for example, Cisapride, Domperidone, Dronedarone. The full list is on the Azithromycin page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
