相互作用
Bupropion + Telotristat etiprate
重症度: 中等度
Bupropion and Telotristat etiprate: moderate interaction.
最終更新日
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概要
Telotristat may induce CYP2B6 and lower exposure to bupropion. This could reduce its antidepressant or smoking-cessation efficacy.
この相互作用をわかりやすく説明すると
Bupropion and Telotristat etiprate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Bupropion belongs to Central Nervous System; Telotristat etiprate belongs to Gastrointestinal Tract.
なぜ起こるのか
Possible CYP2B6 induction increasing bupropion metabolism.
対処法
Monitor clinical response to bupropion and adjust the dose if efficacy declines.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、BupropionとTelotristat etiprateの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Telotristat etiprateのその他の相互作用
Bupropionのその他の相互作用
よくある質問
Can I take Bupropion with Telotristat etiprate?
MediHelp rates the interaction as moderate. Bupropion and Telotristat etiprate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Telotristat may induce CYP2B6 and lower exposure to bupropion. This could reduce its antidepressant or smoking-cessation efficacy.
How serious is the interaction between Bupropion and Telotristat etiprate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor clinical response to bupropion and adjust the dose if efficacy declines.
What other medicines interact with Telotristat etiprate?
MediHelp also lists interactions of Telotristat etiprate with, for example, Capecitabine, Everolimus, Flutamide. The full list is on the Telotristat etiprate page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
