相互作用
Octreotide + Telotristat etiprate
重症度: 中等度
Octreotide and Telotristat etiprate: moderate interaction.
最終更新日
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概要
Short-acting octreotide markedly reduces systemic exposure to telotristat and its active metabolite. This may weaken the control of carcinoid syndrome diarrhoea.
この相互作用をわかりやすく説明すると
Octreotide and Telotristat etiprate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Octreotide belongs to Endocrine; Telotristat etiprate belongs to Gastrointestinal Tract.
なぜ起こるのか
Octreotide's effects on gastrointestinal function reduce telotristat absorption; the exact mechanism is not fully established.
対処法
Give short-acting octreotide at least 30 minutes after telotristat. Monitor bowel movement frequency.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、OctreotideとTelotristat etiprateの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Telotristat etiprateのその他の相互作用
Octreotideのその他の相互作用
よくある質問
Can I take Octreotide with Telotristat etiprate?
MediHelp rates the interaction as moderate. Octreotide and Telotristat etiprate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Short-acting octreotide markedly reduces systemic exposure to telotristat and its active metabolite. This may weaken the control of carcinoid syndrome diarrhoea.
How serious is the interaction between Octreotide and Telotristat etiprate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give short-acting octreotide at least 30 minutes after telotristat. Monitor bowel movement frequency.
What other medicines interact with Telotristat etiprate?
MediHelp also lists interactions of Telotristat etiprate with, for example, Bupropion, Capecitabine, Everolimus. The full list is on the Telotristat etiprate page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
