相互作用
Caspofungin + Efavirenz
重症度: 中等度
Caspofungin and Efavirenz: moderate interaction.
最終更新日
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概要
Efavirenz may lower caspofungin exposure, which could reduce antifungal efficacy. Caspofungin labeling lists efavirenz among inducers for which a higher dose may be considered.
この相互作用をわかりやすく説明すると
Caspofungin and Efavirenz can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Caspofungin belongs to Anti Fungals; Efavirenz belongs to Anti Virals.
なぜ起こるのか
Proposed induction of caspofungin clearance by efavirenz; the exact mechanism is not firmly established.
対処法
Consider increasing caspofungin to 70 mg daily in adults if the response is inadequate, and monitor clinical response.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、CaspofunginとEfavirenzの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Caspofunginのその他の相互作用
Efavirenzのその他の相互作用
よくある質問
Can I take Caspofungin with Efavirenz?
MediHelp rates the interaction as moderate. Caspofungin and Efavirenz can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Efavirenz may lower caspofungin exposure, which could reduce antifungal efficacy. Caspofungin labeling lists efavirenz among inducers for which a higher dose may be considered.
How serious is the interaction between Caspofungin and Efavirenz?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Consider increasing caspofungin to 70 mg daily in adults if the response is inadequate, and monitor clinical response.
What other medicines interact with Caspofungin?
MediHelp also lists interactions of Caspofungin with, for example, Apalutamide, Carbamazepine, Cyclosporin. The full list is on the Caspofungin page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
