相互作用
Ceftazidime + Dexamethasone-tobramycin
重症度: 中等度
Ceftazidime and Dexamethasone-tobramycin: moderate interaction.
最終更新日
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概要
Ceftazidime combined with an aminoglycoside is a common regimen, and reports suggest a possible small increase in kidney injury. Aminoglycoside nephrotoxicity and ototoxicity are the main clinical concern.
この相互作用をわかりやすく説明すると
Ceftazidime and Dexamethasone-tobramycin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Ceftazidime belongs to Anti Bacterial; Dexamethasone-tobramycin belongs to Anti Bacterial.
なぜ起こるのか
Possible additive nephrotoxicity; the mechanism is not firmly established.
対処法
Monitor serum creatinine and urine output, and use tobramycin drug-level monitoring. Reduce dose or interval if renal function declines.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、CeftazidimeとDexamethasone-tobramycinの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Dexamethasone-tobramycinのその他の相互作用
Ceftazidimeのその他の相互作用
よくある質問
Can I take Ceftazidime with Dexamethasone-tobramycin?
MediHelp rates the interaction as moderate. Ceftazidime and Dexamethasone-tobramycin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Ceftazidime combined with an aminoglycoside is a common regimen, and reports suggest a possible small increase in kidney injury. Aminoglycoside nephrotoxicity and ototoxicity are the main clinical concern.
How serious is the interaction between Ceftazidime and Dexamethasone-tobramycin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum creatinine and urine output, and use tobramycin drug-level monitoring. Reduce dose or interval if renal function declines.
What other medicines interact with Dexamethasone-tobramycin?
MediHelp also lists interactions of Dexamethasone-tobramycin with, for example, Capreomycin, Carboplatin, Ciprofloxacin. The full list is on the Dexamethasone-tobramycin page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
