相互作用
Certolizumab pegol + Rotavirus oral vaccine live
重症度: 併用禁忌
Certolizumab pegol and Rotavirus oral vaccine live: contraindicated interaction.
最終更新日
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このページの臨床コンテンツは英語でのみ提供されています。
概要
Oral rotavirus vaccine is a live attenuated virus. Infants exposed to certolizumab, such as through breast milk or in utero, or patients treated directly, may be at risk of vaccine-virus infection, though transfer of certolizumab is minimal.
この相互作用をわかりやすく説明すると
Certolizumab pegol and Rotavirus oral vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
なぜ起こるのか
TNF inhibition impairs immune control of replicating live vaccine virus.
対処法
Avoid rotavirus vaccine in patients receiving certolizumab. For infants of treated mothers, follow current specialist guidance, as certolizumab has minimal placental and milk transfer.
薬剤師に尋ねること
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、Certolizumab pegolとRotavirus oral vaccine liveの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Certolizumab pegolのその他の相互作用
- Adenovirus types 4 and 7 live + Certolizumab pegol 併用禁忌
- Bcg intravesical live + Certolizumab pegol 併用禁忌
- Bcg vaccine live + Certolizumab pegol 併用禁忌
- Certolizumab pegol + Influenza virus vaccine quadrivalent intranasal 併用禁忌
- Certolizumab pegol + Measles mumps and rubella vaccine 併用禁忌
- Certolizumab pegol + Measles mumps and rubella vaccine live 併用禁忌
よくある質問
Can I take Certolizumab pegol with Rotavirus oral vaccine live?
MediHelp rates the interaction as contraindicated. Certolizumab pegol and Rotavirus oral vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Oral rotavirus vaccine is a live attenuated virus. Infants exposed to certolizumab, such as through breast milk or in utero, or patients treated directly, may be at risk of vaccine-virus infection, though transfer of certolizumab is minimal.
How serious is the interaction between Certolizumab pegol and Rotavirus oral vaccine live?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid rotavirus vaccine in patients receiving certolizumab. For infants of treated mothers, follow current specialist guidance, as certolizumab has minimal placental and milk transfer.
What other medicines interact with Certolizumab pegol?
MediHelp also lists interactions of Certolizumab pegol with, for example, Adenovirus types 4 and 7 live, Bcg intravesical live, Bcg vaccine live. The full list is on the Certolizumab pegol page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
