相互作用
Chlorpromazine + Tretinoin
重症度: 中等度
Chlorpromazine and Tretinoin: moderate interaction.
最終更新日
医療従事者向け・参照専用。このページは簡潔な要約であり、医学的助言ではなく、公式の添付文書や臨床判断に代わるものではありません。処方・調剤の前に必ず確認してください。
このページの臨床コンテンツは英語でのみ提供されています。
概要
Chlorpromazine is a well-known photosensitizer, and systemic tretinoin also increases skin sensitivity to ultraviolet light. Together they may cause exaggerated sunburn-like or phototoxic reactions.
この相互作用をわかりやすく説明すると
Chlorpromazine and Tretinoin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Chlorpromazine belongs to Central Nervous System; Tretinoin belongs to Dermatology.
なぜ起こるのか
Additive phototoxicity through different photosensitizing mechanisms.
対処法
Counsel patients to use strict sun protection with broad-spectrum sunscreen and protective clothing. Review the skin if a reaction develops.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、ChlorpromazineとTretinoinの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
WebでPro+を7日間無料でお試し。カード登録不要。
Chlorpromazineのその他の相互作用
Tretinoinのその他の相互作用
よくある質問
Can I take Chlorpromazine with Tretinoin?
MediHelp rates the interaction as moderate. Chlorpromazine and Tretinoin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Chlorpromazine is a well-known photosensitizer, and systemic tretinoin also increases skin sensitivity to ultraviolet light. Together they may cause exaggerated sunburn-like or phototoxic reactions.
How serious is the interaction between Chlorpromazine and Tretinoin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel patients to use strict sun protection with broad-spectrum sunscreen and protective clothing. Review the skin if a reaction develops.
What other medicines interact with Chlorpromazine?
MediHelp also lists interactions of Chlorpromazine with, for example, Dofetilide, Dronedarone, Droperidol. The full list is on the Chlorpromazine page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
