相互作用
Cisapride + Hydroxychloroquine
重症度: 併用禁忌
Cisapride and Hydroxychloroquine: contraindicated interaction.
最終更新日
医療従事者向け・参照専用。このページは簡潔な要約であり、医学的助言ではなく、公式の添付文書や臨床判断に代わるものではありません。処方・調剤の前に必ず確認してください。
このページの臨床コンテンツは英語でのみ提供されています。
概要
Hydroxychloroquine can prolong the QT interval and, with cisapride, increases the risk of torsades de pointes.
この相互作用をわかりやすく説明すると
Cisapride and Hydroxychloroquine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Cisapride belongs to Gastrointestinal Tract; Hydroxychloroquine belongs to Musculoskeletal.
なぜ起こるのか
Additive inhibition of cardiac potassium channels with QT prolongation.
対処法
Avoid the combination and use an alternative prokinetic. If unavoidable, monitor the ECG and keep potassium and magnesium within normal limits.
薬剤師に尋ねること
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、CisaprideとHydroxychloroquineの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
WebでPro+を14日間無料でお試し。カード登録不要。
Cisaprideのその他の相互作用
Hydroxychloroquineのその他の相互作用
よくある質問
Can I take Cisapride with Hydroxychloroquine?
MediHelp rates the interaction as contraindicated. Cisapride and Hydroxychloroquine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Hydroxychloroquine can prolong the QT interval and, with cisapride, increases the risk of torsades de pointes.
How serious is the interaction between Cisapride and Hydroxychloroquine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination and use an alternative prokinetic. If unavoidable, monitor the ECG and keep potassium and magnesium within normal limits.
What other medicines interact with Cisapride?
MediHelp also lists interactions of Cisapride with, for example, Apomorphine, Artemether, Azithromycin. The full list is on the Cisapride page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
