相互作用
Dronedarone + Hydroxychloroquine
重症度: 併用禁忌
Dronedarone and Hydroxychloroquine: contraindicated interaction.
最終更新日
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概要
Dronedarone prolongs the QT interval and hydroxychloroquine adds to this effect, increasing the risk of torsades de pointes. Dronedarone's labeling advises against combination with QT-prolonging drugs.
この相互作用をわかりやすく説明すると
Dronedarone and Hydroxychloroquine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Dronedarone belongs to Cardiovascular; Hydroxychloroquine belongs to Musculoskeletal.
なぜ起こるのか
Additive delayed ventricular repolarization through potassium channel blockade.
対処法
Do not combine; choose an alternative antiarrhythmic or an alternative to hydroxychloroquine.
薬剤師に尋ねること
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、DronedaroneとHydroxychloroquineの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Hydroxychloroquineのその他の相互作用
Dronedaroneのその他の相互作用
よくある質問
Can I take Dronedarone with Hydroxychloroquine?
MediHelp rates the interaction as contraindicated. Dronedarone and Hydroxychloroquine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Dronedarone prolongs the QT interval and hydroxychloroquine adds to this effect, increasing the risk of torsades de pointes. Dronedarone's labeling advises against combination with QT-prolonging drugs.
How serious is the interaction between Dronedarone and Hydroxychloroquine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not combine; choose an alternative antiarrhythmic or an alternative to hydroxychloroquine.
What other medicines interact with Hydroxychloroquine?
MediHelp also lists interactions of Hydroxychloroquine with, for example, Arsenic trioxide, Cisapride, Pimozide. The full list is on the Hydroxychloroquine page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
