相互作用
Colesevelam + Paricalcitol
重症度: 軽度
Colesevelam and Paricalcitol: minor interaction.
最終更新日
医療従事者向け・参照専用。このページは簡潔な要約であり、医学的助言ではなく、公式の添付文書や臨床判断に代わるものではありません。処方・調剤の前に必ず確認してください。
このページの臨床コンテンツは英語でのみ提供されています。
概要
Bile acid sequestrants may reduce absorption of fat-soluble vitamin D analogs, potentially lessening the effect of oral paricalcitol on PTH suppression.
この相互作用をわかりやすく説明すると
Colesevelam and Paricalcitol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Colesevelam belongs to Endocrine; Paricalcitol belongs to Musculoskeletal.
なぜ起こるのか
Colesevelam binds the lipophilic vitamin D analog in the gut and may reduce bile-dependent absorption.
対処法
Separate paricalcitol from colesevelam by at least 4 hours and monitor PTH and calcium.
薬剤師に尋ねること
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、ColesevelamとParicalcitolの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Colesevelamのその他の相互作用
Paricalcitolのその他の相互作用
よくある質問
Can I take Colesevelam with Paricalcitol?
MediHelp rates the interaction as minor. Colesevelam and Paricalcitol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Bile acid sequestrants may reduce absorption of fat-soluble vitamin D analogs, potentially lessening the effect of oral paricalcitol on PTH suppression.
How serious is the interaction between Colesevelam and Paricalcitol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Separate paricalcitol from colesevelam by at least 4 hours and monitor PTH and calcium.
What other medicines interact with Colesevelam?
MediHelp also lists interactions of Colesevelam with, for example, Amlodipine-olmesartan-hydrochlorothiazide, Amlodipine-olmesartan, Chenodiol. The full list is on the Colesevelam page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
