相互作用
Desogestrel-ethinyl estradiol + Lesinurad
重症度: 中等度
Desogestrel-ethinyl estradiol and Lesinurad: moderate interaction.
最終更新日
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概要
Lesinurad can reduce exposure to ethinyl estradiol and progestins, so hormonal contraceptives may be less effective. Lesinurad has been discontinued from the market, so this is now of limited practical relevance.
この相互作用をわかりやすく説明すると
Desogestrel-ethinyl estradiol and Lesinurad can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Desogestrel-ethinyl estradiol belongs to Endocrine; Lesinurad belongs to Genitourinary.
なぜ起こるのか
Lesinurad is a weak CYP3A inducer that may lower contraceptive steroid concentrations.
対処法
Recommend an additional non-hormonal contraceptive method if the combination is encountered. Do not rely on hormonal contraception alone.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、Desogestrel-ethinyl estradiolとLesinuradの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Desogestrel-ethinyl estradiolのその他の相互作用
Lesinuradのその他の相互作用
よくある質問
Can I take Desogestrel-ethinyl estradiol with Lesinurad?
MediHelp rates the interaction as moderate. Desogestrel-ethinyl estradiol and Lesinurad can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Lesinurad can reduce exposure to ethinyl estradiol and progestins, so hormonal contraceptives may be less effective. Lesinurad has been discontinued from the market, so this is now of limited practical relevance.
How serious is the interaction between Desogestrel-ethinyl estradiol and Lesinurad?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Recommend an additional non-hormonal contraceptive method if the combination is encountered. Do not rely on hormonal contraception alone.
What other medicines interact with Desogestrel-ethinyl estradiol?
MediHelp also lists interactions of Desogestrel-ethinyl estradiol with, for example, Fezolinetant, Aminocaproic acid, Amobarbital. The full list is on the Desogestrel-ethinyl estradiol page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
