相互作用
Dicyclomine + Revefenacin
重症度: 中等度
Dicyclomine and Revefenacin: moderate interaction.
最終更新日
医療従事者向け・参照専用。このページは簡潔な要約であり、医学的助言ではなく、公式の添付文書や臨床判断に代わるものではありません。処方・調剤の前に必ず確認してください。
このページの臨床コンテンツは英語でのみ提供されています。
概要
Revefenacin is an inhaled long-acting muscarinic antagonist with low systemic exposure. Combined with oral dicyclomine, additive anticholinergic effects may occur, such as dry mouth, urinary retention and constipation.
この相互作用をわかりやすく説明すると
Dicyclomine and Revefenacin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Dicyclomine belongs to Respiratory; Revefenacin belongs to Respiratory.
なぜ起こるのか
Additive antimuscarinic effects at peripheral cholinergic receptors.
対処法
Monitor for urinary retention, constipation, dry mouth and narrow-angle glaucoma symptoms. Reduce or stop dicyclomine if anticholinergic effects develop.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、DicyclomineとRevefenacinの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
WebでPro+を7日間無料でお試し。カード登録不要。
Dicyclomineのその他の相互作用
Revefenacinのその他の相互作用
よくある質問
Can I take Dicyclomine with Revefenacin?
MediHelp rates the interaction as moderate. Dicyclomine and Revefenacin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Revefenacin is an inhaled long-acting muscarinic antagonist with low systemic exposure. Combined with oral dicyclomine, additive anticholinergic effects may occur, such as dry mouth, urinary retention and constipation.
How serious is the interaction between Dicyclomine and Revefenacin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for urinary retention, constipation, dry mouth and narrow-angle glaucoma symptoms. Reduce or stop dicyclomine if anticholinergic effects develop.
What other medicines interact with Dicyclomine?
MediHelp also lists interactions of Dicyclomine with, for example, Clozapine, Henbane, Imipramine. The full list is on the Dicyclomine page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。