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相互作用

Ethinyl estradiol-norgestimate + Mineral oil

重症度: 軽度

Ethinyl estradiol-norgestimate and Mineral oil: minor interaction.

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概要

Oral mineral oil may dissolve fat-soluble substances in the gut and reduce absorption of lipophilic steroid hormones. In theory this could lower contraceptive hormone exposure, though clinical significance is uncertain with occasional use.

この相互作用をわかりやすく説明すると

Ethinyl estradiol-norgestimate and Mineral oil have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Ethinyl estradiol-norgestimate belongs to Endocrine; Mineral oil belongs to Gastrointestinal Tract.

エビデンスレベル: Low

なぜ起こるのか

Mineral oil acts as a lipid solvent in the intestinal lumen, which may reduce absorption of lipophilic drugs.

対処法

Avoid regular use of mineral oil and take the contraceptive at least 2 hours before or after any dose. Counsel the patient to use backup contraception if prolonged diarrhea or heavy laxative use occurs.

薬剤師に尋ねること

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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アカウントを作成してPro+トライアルを始めると、Ethinyl estradiol-norgestimateとMineral oilの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。

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  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

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よくある質問

Can I take Ethinyl estradiol-norgestimate with Mineral oil?

MediHelp rates the interaction as minor. Ethinyl estradiol-norgestimate and Mineral oil have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Oral mineral oil may dissolve fat-soluble substances in the gut and reduce absorption of lipophilic steroid hormones. In theory this could lower contraceptive hormone exposure, though clinical significance is uncertain with occasional use.

How serious is the interaction between Ethinyl estradiol-norgestimate and Mineral oil?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid regular use of mineral oil and take the contraceptive at least 2 hours before or after any dose. Counsel the patient to use backup contraception if prolonged diarrhea or heavy laxative use occurs.

What other medicines interact with Ethinyl estradiol-norgestimate?

MediHelp also lists interactions of Ethinyl estradiol-norgestimate with, for example, Fezolinetant, Ombitasvir / paritaprevir / ritonavir and dasabuvir, Tranexamic acid. The full list is on the Ethinyl estradiol-norgestimate page.

完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで

MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。

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