Interações medicamentosas
Amoxicillin-clavulanic acid + Tetracycline
Gravidade: Moderada
Amoxicillin-clavulanic acid and Tetracycline: moderate interaction.
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Resumo
Bacteriostatic tetracyclines may blunt the bactericidal activity of beta-lactams, which depend on actively growing bacteria. Clinical evidence is mostly from older studies in serious infections such as meningitis.
O que esta interação significa em palavras simples
Amoxicillin-clavulanic acid and Tetracycline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Amoxicillin-clavulanic acid belongs to Anti Bacterial; Tetracycline belongs to Anti Bacterial.
Por que acontece
Tetracycline-induced inhibition of bacterial protein synthesis and growth reduces beta-lactam killing, which requires cell wall synthesis.
O que fazer
Avoid the combination in severe infections where bactericidal activity is essential. Otherwise monitor clinical response.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Amoxicillin-clavulanic acid
- Amoxicillin-clavulanic acid + Methotrexate Grave
- Amoxicillin-clavulanic acid + Pexidartinib Grave
- Amoxicillin-clavulanic acid + Pretomanid Grave
- Allopurinol + Amoxicillin-clavulanic acid Moderada
- Amoxicillin-clavulanic acid + Bcg vaccine live Moderada
- Amoxicillin-clavulanic acid + Chloramphenicol Moderada
Outras interações de Tetracycline
- Acitretin + Tetracycline Contraindicada
- Methoxyflurane + Tetracycline Contraindicada
- Isotretinoin + Tetracycline Grave
- Palovarotene + Tetracycline Grave
- Strontium ranelate + Tetracycline Grave
- Tetracycline + Tretinoin Grave
Perguntas frequentes
Can I take Amoxicillin-clavulanic acid with Tetracycline?
MediHelp rates the interaction as moderate. Amoxicillin-clavulanic acid and Tetracycline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Bacteriostatic tetracyclines may blunt the bactericidal activity of beta-lactams, which depend on actively growing bacteria. Clinical evidence is mostly from older studies in serious infections such as meningitis.
How serious is the interaction between Amoxicillin-clavulanic acid and Tetracycline?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination in severe infections where bactericidal activity is essential. Otherwise monitor clinical response.
What other medicines interact with Amoxicillin-clavulanic acid?
MediHelp also lists interactions of Amoxicillin-clavulanic acid with, for example, Methotrexate, Pexidartinib, Pretomanid. The full list is on the Amoxicillin-clavulanic acid page.
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