Interações medicamentosas
Ephedrine + Procarbazine
Gravidade: Contraindicada
Ephedrine and Procarbazine: contraindicated interaction.
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Resumo
Ephedrine releases noradrenaline indirectly, and procarbazine inhibits MAO, so the pressor response may be markedly exaggerated. This may cause a hypertensive crisis, severe headache, and arrhythmias.
O que esta interação significa em palavras simples
Ephedrine and Procarbazine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Ephedrine belongs to Cardiovascular; Procarbazine belongs to Oncology.
Por que acontece
MAO inhibition increases neuronal noradrenaline stores and prolongs the effect of indirect sympathomimetics.
O que fazer
Avoid ephedrine and other sympathomimetics during and for 14 days after procarbazine. Use non-pressor alternatives for symptom relief.
O que perguntar ao farmacêutico
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Outras interações de Procarbazine
- Adenovirus types 4 and 7 live + Procarbazine Contraindicada
- Amitriptyline + Procarbazine Contraindicada
- Amoxapine + Procarbazine Contraindicada
- Atomoxetine + Procarbazine Contraindicada
- Bcg vaccine live + Procarbazine Contraindicada
- Brimonidine + Procarbazine Contraindicada
Outras interações de Ephedrine
- Ephedrine + Isocarboxazid Contraindicada
- Ephedrine + Phenelzine Contraindicada
- Ephedrine + Rasagiline Contraindicada
- Ephedrine + Selegiline Contraindicada
- Ephedrine + Tranylcypromine Contraindicada
- Caffeine + Ephedrine Grave
Perguntas frequentes
Can I take Ephedrine with Procarbazine?
MediHelp rates the interaction as contraindicated. Ephedrine and Procarbazine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Ephedrine releases noradrenaline indirectly, and procarbazine inhibits MAO, so the pressor response may be markedly exaggerated. This may cause a hypertensive crisis, severe headache, and arrhythmias.
How serious is the interaction between Ephedrine and Procarbazine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid ephedrine and other sympathomimetics during and for 14 days after procarbazine. Use non-pressor alternatives for symptom relief.
What other medicines interact with Procarbazine?
MediHelp also lists interactions of Procarbazine with, for example, Adenovirus types 4 and 7 live, Amitriptyline, Amoxapine. The full list is on the Procarbazine page.
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