Interações medicamentosas
Carbamazepine + Caspofungin
Gravidade: Moderada
Carbamazepine and Caspofungin: moderate interaction.
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Resumo
Carbamazepine, an enzyme inducer, may lower caspofungin concentrations and reduce antifungal efficacy. Labeling suggests considering a higher caspofungin dose with inducers such as carbamazepine.
O que esta interação significa em palavras simples
Carbamazepine and Caspofungin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Carbamazepine belongs to Central Nervous System; Caspofungin belongs to Anti Fungals.
Por que acontece
Induction of caspofungin clearance by carbamazepine.
O que fazer
Consider a caspofungin maintenance dose of 70 mg daily in adults when given with carbamazepine, and monitor clinical response.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Caspofungin
- Apalutamide + Caspofungin Moderada
- Caspofungin + Cyclosporin Moderada
- Caspofungin + Cyclosporine Moderada
- Caspofungin + Dexamethasone Moderada
- Caspofungin + Efavirenz Moderada
- Caspofungin + Fosphenytoin Moderada
Outras interações de Carbamazepine
- Artemether / lumefantrine + Carbamazepine Contraindicada
- Cabotegravir + Carbamazepine Contraindicada
- Carbamazepine + Delamanid Contraindicada
- Carbamazepine + Dienogest / estradiol valerate Contraindicada
- Carbamazepine + Doravirine Contraindicada
- Carbamazepine + Elbasvir / grazoprevir Contraindicada
Perguntas frequentes
Can I take Carbamazepine with Caspofungin?
MediHelp rates the interaction as moderate. Carbamazepine and Caspofungin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Carbamazepine, an enzyme inducer, may lower caspofungin concentrations and reduce antifungal efficacy. Labeling suggests considering a higher caspofungin dose with inducers such as carbamazepine.
How serious is the interaction between Carbamazepine and Caspofungin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Consider a caspofungin maintenance dose of 70 mg daily in adults when given with carbamazepine, and monitor clinical response.
What other medicines interact with Caspofungin?
MediHelp also lists interactions of Caspofungin with, for example, Apalutamide, Cyclosporin, Cyclosporine. The full list is on the Caspofungin page.
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