Interações medicamentosas
Cisatracurium + Lincomycin
Gravidade: Grave
Cisatracurium and Lincomycin: major interaction.
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Resumo
Lincomycin has neuromuscular blocking activity and can potentiate non-depolarizing relaxants such as cisatracurium. This can prolong paralysis and delay return of spontaneous ventilation.
O que esta interação significa em palavras simples
Cisatracurium and Lincomycin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Cisatracurium belongs to Musculoskeletal; Lincomycin belongs to Anti Bacterial.
Por que acontece
Additive neuromuscular blockade via presynaptic and postsynaptic inhibition of transmission by lincomycin.
O que fazer
Monitor train-of-four and titrate cisatracurium cautiously. Keep ventilatory support available until full recovery of neuromuscular function.
O que perguntar ao farmacêutico
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Outras interações de Cisatracurium
Outras interações de Lincomycin
- Atracurium + Lincomycin Grave
- Lincomycin + Pancuronium Grave
- Lincomycin + Rapacuronium Grave
- Lincomycin + Rocuronium Grave
- Lincomycin + Vecuronium Grave
- Cholera vaccine + Lincomycin Moderada
Perguntas frequentes
Can I take Cisatracurium with Lincomycin?
MediHelp rates the interaction as major. Cisatracurium and Lincomycin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Lincomycin has neuromuscular blocking activity and can potentiate non-depolarizing relaxants such as cisatracurium. This can prolong paralysis and delay return of spontaneous ventilation.
How serious is the interaction between Cisatracurium and Lincomycin?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor train-of-four and titrate cisatracurium cautiously. Keep ventilatory support available until full recovery of neuromuscular function.
What other medicines interact with Cisatracurium?
MediHelp also lists interactions of Cisatracurium with, for example, Amikacin, Bacitracin-neomycin-polymyxin, Benzhydrocodone / acetaminophen. The full list is on the Cisatracurium page.
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