Interações medicamentosas
Lincomycin + Pancuronium
Gravidade: Grave
Lincomycin and Pancuronium: major interaction.
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Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.
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Resumo
Lincomycin can potentiate pancuronium and prolong neuromuscular blockade. Delayed recovery and respiratory depression have been described with this class combination.
O que esta interação significa em palavras simples
Lincomycin and Pancuronium can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Lincomycin belongs to Anti Bacterial; Pancuronium belongs to Musculoskeletal.
Por que acontece
Lincomycin has weak intrinsic neuromuscular blocking activity that adds to pancuronium's effect.
O que fazer
Titrate pancuronium with train-of-four monitoring and maintain ventilatory support until recovery is confirmed. Choose a different antibiotic if practical.
O que perguntar ao farmacêutico
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Outras interações de Pancuronium
Outras interações de Lincomycin
- Atracurium + Lincomycin Grave
- Cisatracurium + Lincomycin Grave
- Lincomycin + Rapacuronium Grave
- Lincomycin + Rocuronium Grave
- Lincomycin + Vecuronium Grave
- Cholera vaccine + Lincomycin Moderada
Perguntas frequentes
Can I take Lincomycin with Pancuronium?
MediHelp rates the interaction as major. Lincomycin and Pancuronium can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Lincomycin can potentiate pancuronium and prolong neuromuscular blockade. Delayed recovery and respiratory depression have been described with this class combination.
How serious is the interaction between Lincomycin and Pancuronium?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Titrate pancuronium with train-of-four monitoring and maintain ventilatory support until recovery is confirmed. Choose a different antibiotic if practical.
What other medicines interact with Pancuronium?
MediHelp also lists interactions of Pancuronium with, for example, Amikacin, Bacitracin-neomycin-polymyxin, Capreomycin. The full list is on the Pancuronium page.
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