Interações medicamentosas
Ephedrine + Ergotamine
Gravidade: Grave
Ephedrine and Ergotamine: major interaction.
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Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.
O conteúdo clínico desta página está disponível apenas em inglês.
Resumo
Ephedrine is a sympathomimetic with pressor and vasoconstrictor effects. Combined with ergotamine it may cause excessive vasoconstriction, severe hypertension and ischemia.
O que esta interação significa em palavras simples
Ephedrine and Ergotamine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Ephedrine belongs to Cardiovascular; Ergotamine belongs to Central Nervous System.
Por que acontece
Additive alpha-adrenergic and ergot-mediated vasoconstriction.
O que fazer
Avoid the combination; if ephedrine is needed, monitor blood pressure and peripheral perfusion closely.
O que perguntar ao farmacêutico
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Outras interações de Ergotamine
- Almotriptan + Ergotamine Contraindicada
- Atazanavir + Ergotamine Contraindicada
- Clarithromycin + Ergotamine Contraindicada
- Cobicistat + Ergotamine Contraindicada
- Darunavir + Ergotamine Contraindicada
- Dihydroergotamine intranasal + Ergotamine Contraindicada
Outras interações de Ephedrine
- Ephedrine + Isocarboxazid Contraindicada
- Ephedrine + Phenelzine Contraindicada
- Ephedrine + Procarbazine Contraindicada
- Ephedrine + Rasagiline Contraindicada
- Ephedrine + Selegiline Contraindicada
- Ephedrine + Tranylcypromine Contraindicada
Perguntas frequentes
Can I take Ephedrine with Ergotamine?
MediHelp rates the interaction as major. Ephedrine and Ergotamine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Ephedrine is a sympathomimetic with pressor and vasoconstrictor effects. Combined with ergotamine it may cause excessive vasoconstriction, severe hypertension and ischemia.
How serious is the interaction between Ephedrine and Ergotamine?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination; if ephedrine is needed, monitor blood pressure and peripheral perfusion closely.
What other medicines interact with Ergotamine?
MediHelp also lists interactions of Ergotamine with, for example, Almotriptan, Atazanavir, Clarithromycin. The full list is on the Ergotamine page.
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