藥品參考
Apraclonidine
Apraclonidine is a medicine in the class cardiovascular. It is used for ocular hypertension.
- 藥物類別: Cardiovascular
- 用途: ocular hypertension
最後更新 來源: US FDA label
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本頁的臨床內容僅提供英文版。
重點資訊
- 藥物類別
- Cardiovascular
- 常見劑型
- 滴劑
- 常見規格
- 10 mg/ml
- 已知交互作用
- 6 (禁忌併用: 1 · 嚴重: 5)
- 商品名
- 2
- 國家與市場
- 2
用途
作用方式
Relatively selective alpha adrenergic agonist without significant membrane stabilizing (local anesthetic) activity; reduces intraocular pressure, predominantly by reducing aqueous formation (mechanism not completely established).
成人常用劑量（仿單摘要）
Prevention or control of post-surgical IOP elevation after anterior segment laser surgery: 1 drop in the scheduled operative eye one hour before surgery, then a second drop immediately upon completion of the procedure; ophthalmic.
懷孕與哺乳
- 懷孕
- Unknown Eye drops: no adequate human studies; embryocidal in rabbits only at high oral doses. Use only if benefit justifies risk. Press on the tear duct after each drop to reduce absorption.
- 哺乳
- Unknown Eye drops: unknown if it passes into milk. Label suggests stopping breastfeeding on the day of use. Related clonidine passes into milk; watch the infant for drowsiness. Press on the tear duct after drops.
已通報的副作用
- Conjunctival blanching
- Upper lid elevation
- Mydriasis
- Ocular injection
- Dry mouth
- Headache
禁忌症
- Patients receiving monoamine oxidase inhibitor therapy.
- Hypersensitivity to any component of the medication or to clonidine.
哪些人需要特別留意
- For topical ophthalmic use only; not for injection or oral ingestion.
- Cardiovascular collapse requiring intubation and ventilation and other systemic reactions reported in pediatric patients 6 years and younger, including neonates; appropriate clinical monitoring should be in place.
- Patients with exaggerated IOP reductions should be closely monitored.
請告知藥師或醫師您是否懷孕或哺乳、是否患有腎臟或肝臟疾病、是否有過敏，以及您正在使用的所有其他藥物或保健品。
重要交互作用 (6)
- Apraclonidine + Isocarboxazid Contraindicated
- Apraclonidine + Linezolid Major
- Apraclonidine + Phenelzine Major
- Apraclonidine + Rasagiline Major
- Apraclonidine + Selegiline Major
- Apraclonidine + Tranylcypromine Major
同類別的其他藥品
常見問題
What is Apraclonidine used for?
Apraclonidine is a medicine in the class cardiovascular. It is used for Ocular hypertension.
What side effects have been reported with Apraclonidine?
Conjunctival blanching, Upper lid elevation, Mydriasis, Ocular injection, Dry mouth, Headache.
Can Apraclonidine be taken in pregnancy or while breastfeeding?
Pregnancy: Unknown. Eye drops: no adequate human studies; embryocidal in rabbits only at high oral doses. Use only if benefit justifies risk. Press on the tear duct after each drop to reduce absorption. Breastfeeding: Unknown. Eye drops: unknown if it passes into milk. Label suggests stopping breastfeeding on the day of use. Related clonidine passes into milk; watch the infant for drowsiness. Press on the tear duct after drops.
What does Apraclonidine interact with?
MediHelp lists 6 known interactions for Apraclonidine. Contraindicated: 1 · Major: 5. The most serious include Isocarboxazid, Linezolid, Phenelzine.
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