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藥品參考

Guanfacine

Guanfacine is a medicine in the class cardiovascular. It is used for adhd.

最後更新 來源: US FDA label

僅供醫療專業人員參考。本頁為簡要摘要,並非醫療建議,亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。

本頁的臨床內容僅提供英文版。

重點資訊

藥物類別
Cardiovascular
ATC 代碼
C02AC02
常見劑型
錠劑
已知交互作用
136 (嚴重: 2 · 中度: 95 · 輕微: 39)
商品名
4
國家與市場
2

劑型、規格與商品名稱會因國家而異。請核對您手上的產品。

用途

作用方式

Central alpha 2A-adrenergic receptor agonist; not a CNS stimulant. Its mechanism of action in ADHD is not known.

懷孕與哺乳

懷孕
Unknown Available data over decades have not identified a drug-associated risk of major birth defects, miscarriage or adverse outcomes, but use in pregnancy has been infrequent.
哺乳
Unknown No human milk data; present in rat milk. Monitor infants for sedation, lethargy and poor feeding.

已通報的副作用

  • Somnolence
  • Fatigue
  • Hypotension
  • Nausea
  • Lethargy
  • Abdominal pain

禁忌症

  • History of hypersensitivity to INTUNIV, its inactive ingredients, or other guanfacine products.

哪些人需要特別留意

  • Hypotension, bradycardia, syncope: dose-dependent; measure heart rate and blood pressure before starting, after dose increases and periodically; titrate slowly in at-risk patients.
  • Sedation and somnolence are common; additive effects with CNS depressants; caution with driving or heavy equipment; avoid alcohol.
  • May worsen sinus node dysfunction and AV block, especially with other sympatholytic drugs.

請告知藥師或醫師您是否懷孕或哺乳、是否患有腎臟或肝臟疾病、是否有過敏,以及您正在使用的所有其他藥物或保健品。

重要交互作用 (136)

All 136 interactions, with severity and what to do

Pro+ 會員專屬

解鎖完整頁面

建立帳號並開始 Pro+ 試用,即可開啟 Guanfacine 的完整藥品專論:劑量、懷孕與哺乳、副作用、警示及所有交互作用。

  • Dosing by age, kidney and liver function, and further dose lines
  • Renal and hepatic dose adjustments
  • Paediatric dosing
  • Dosing in older adults
  • How to give it
  • Pharmacokinetics
  • Patient counselling points
  • Food interactions

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同類別的其他藥品

相關快速閱讀

常見問題

What is Guanfacine used for?

Guanfacine is a medicine in the class cardiovascular. It is used for ADHD.

What side effects have been reported with Guanfacine?

Somnolence, Fatigue, Hypotension, Nausea, Lethargy, Abdominal pain.

Can Guanfacine be taken in pregnancy or while breastfeeding?

Pregnancy: Unknown. Available data over decades have not identified a drug-associated risk of major birth defects, miscarriage or adverse outcomes, but use in pregnancy has been infrequent. Breastfeeding: Unknown. No human milk data; present in rat milk. Monitor infants for sedation, lethargy and poor feeding.

What does Guanfacine interact with?

MediHelp lists 136 known interactions for Guanfacine. Major: 2 · Moderate: 95 · Minor: 39. The most serious include Clonidine, Lofexidine, Aldesleukin.

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