藥品參考
Revefenacin
Revefenacin is a medicine in the class respiratory. It is used for copd.
- 藥物類別: Respiratory
- 用途: copd
最後更新 來源: US FDA label
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
重點資訊
- 藥物類別
- Respiratory
- 常見劑型
- 溶液
- 常見規格
- 175 mcg/3 ml
- 已知交互作用
- 25 (嚴重: 4 · 中度: 20 · 輕微: 1)
- 商品名
- 2
- 國家與市場
- 2
用途
作用方式
Long-acting muscarinic antagonist (anticholinergic) with similar affinity for muscarinic receptor subtypes M1 to M5. In the airways it inhibits M3 receptors at the smooth muscle, leading to bronchodilation.
成人常用劑量（仿單摘要）
COPD maintenance: 175 mcg (one 175 mcg unit-dose vial, 3 mL), oral inhalation by jet nebulizer with mouthpiece, once daily
懷孕與哺乳
- 懷孕
- Unknown Inhaled; no adequate human data. No birth defects or fetal deaths in rats or rabbits at over 200 times human exposure. Women should tell their doctor if pregnant; continue only if the COPD benefit outweighs the risk.
- 哺乳
- Safe Not known if it passes into human milk; rat milk levels were up to 10 times plasma. Only about 3% is absorbed orally, so infant effects are unlikely (LactMed). Long-term use might reduce milk supply; watch the infant's feeding and weight.
已通報的副作用
- Cough
- Nasopharyngitis
- Upper respiratory tract infection
- Headache
- Back pain
- Dry mouth (postmarketing)
禁忌症
- Hypersensitivity to revefenacin or any component of the product.
哪些人需要特別留意
- Do not initiate in acutely deteriorating COPD or use for acute symptoms or as rescue therapy; extra doses should not be used.
- Paradoxical bronchospasm may be life-threatening; treat with a short-acting bronchodilator, discontinue YUPELRI and institute alternative therapy.
- Use with caution in narrow-angle glaucoma; patients should report symptoms immediately.
請告知藥師或醫師您是否懷孕或哺乳、是否患有腎臟或肝臟疾病、是否有過敏，以及您正在使用的所有其他藥物或保健品。
重要交互作用 (25)
- Cyclosporin + Revefenacin Major
- Indacaterol-glycopyrronium + Revefenacin Major
- Revefenacin + Rifampicin Major
- Revefenacin + Tiotropium Major
- Atropine + Revefenacin Moderate
- Benztropine + Revefenacin Moderate
- Darifenacin + Revefenacin Moderate
- Dicyclomine + Revefenacin Moderate
- Diphenoxylate-atropine + Revefenacin Moderate
- Erythromycin + Revefenacin Moderate
同類別的其他藥品
常見問題
What is Revefenacin used for?
Revefenacin is a medicine in the class respiratory. It is used for COPD.
What side effects have been reported with Revefenacin?
Cough, Nasopharyngitis, Upper respiratory tract infection, Headache, Back pain, Dry mouth (postmarketing).
Can Revefenacin be taken in pregnancy or while breastfeeding?
Pregnancy: Unknown. Inhaled; no adequate human data. No birth defects or fetal deaths in rats or rabbits at over 200 times human exposure. Women should tell their doctor if pregnant; continue only if the COPD benefit outweighs the risk. Breastfeeding: Safe. Not known if it passes into human milk; rat milk levels were up to 10 times plasma. Only about 3% is absorbed orally, so infant effects are unlikely (LactMed). Long-term use might reduce milk supply; watch the infant's feeding and weight.
What does Revefenacin interact with?
MediHelp lists 25 known interactions for Revefenacin. Major: 4 · Moderate: 20 · Minor: 1. The most serious include Cyclosporin, Indacaterol-glycopyrronium, Rifampicin.
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