藥物交互作用
Erythromycin + Revefenacin
嚴重程度: 中度
Erythromycin and Revefenacin: moderate interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Erythromycin inhibits OATP1B1 and OATP1B3 transport, which may raise exposure to revefenacin's active metabolite. Increased systemic anticholinergic effects such as dry mouth, urinary retention and tachycardia may occur.
用白話說明這項交互作用的意義
Erythromycin and Revefenacin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Erythromycin belongs to Anti Bacterial; Revefenacin belongs to Respiratory.
為什麼會發生
Inhibition of hepatic OATP1B1/1B3 uptake increases systemic exposure to revefenacin's active metabolite.
處置方式
Prefer an alternative antibiotic when possible. If combined, monitor for systemic anticholinergic effects.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Erythromycin 的其他交互作用
Revefenacin 的其他交互作用
常見問題
Can I take Erythromycin with Revefenacin?
MediHelp rates the interaction as moderate. Erythromycin and Revefenacin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Erythromycin inhibits OATP1B1 and OATP1B3 transport, which may raise exposure to revefenacin's active metabolite. Increased systemic anticholinergic effects such as dry mouth, urinary retention and tachycardia may occur.
How serious is the interaction between Erythromycin and Revefenacin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Prefer an alternative antibiotic when possible. If combined, monitor for systemic anticholinergic effects.
What other medicines interact with Erythromycin?
MediHelp also lists interactions of Erythromycin with, for example, Conivaptan, Dihydroergotamine intranasal, Dihydroergotamine. The full list is on the Erythromycin page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
