藥品參考
Glycopyrrolate
Glycopyrrolate is a medicine in the class respiratory.
- 藥物類別: Respiratory
最後更新 來源: US FDA label
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
重點資訊
- 藥物類別
- Respiratory
- 常見劑型
- 錠劑, 溶液
- 常見規格
- 1 mg/5 ml, 1.5 mg
- 已知交互作用
- 80 (嚴重: 1 · 中度: 48 · 輕微: 31)
- 商品名
- 2
- 國家與市場
- 1
作用方式
Competitive inhibitor of acetylcholine receptors on certain peripheral tissues, including salivary glands; indirectly reduces the rate of salivation by preventing stimulation of these receptors.
懷孕與哺乳
- 懷孕
- Unknown Injection: very little crosses the placenta; widely used in anaesthesia, including caesarean section, without fetal heart effects. Oral and inhaled forms: no human data; no birth defects in rats or rabbits. Some UK injection labels: not recommended. Use only if clearly needed.
- 哺乳
- Safe No milk data; it is poorly absorbed by the infant (quaternary drug). Single doses (e.g. anaesthesia) and inhaled or skin use are unlikely to matter. Long-term oral use may reduce milk supply; watch the infant's weight gain.
已通報的副作用
- Dry mouth
- Vomiting
- Constipation
- Flushing
- Nasal congestion
- Urinary retention
禁忌症
- Medical conditions that preclude anticholinergic therapy (e.g., glaucoma, paralytic ileus, unstable cardiovascular status in acute hemorrhage, severe ulcerative colitis, toxic megacolon, myasthenia gravis).
- Concomitant solid oral dosage forms of potassium chloride.
哪些人需要特別留意
- Constipation or intestinal pseudo-obstruction: assess for constipation, particularly within 4-5 days of initial dosing or after a dose increase.
- Diarrhea may signal incomplete mechanical intestinal obstruction; if suspected, discontinue and evaluate.
- Heat prostration can occur in high ambient temperature; avoid hot environments.
請告知藥師或醫師您是否懷孕或哺乳、是否患有腎臟或肝臟疾病、是否有過敏，以及您正在使用的所有其他藥物或保健品。
重要交互作用 (80)
- Glycopyrrolate + Potassium chloride Major
- Amitriptyline + Glycopyrrolate Moderate
- Atropine + Glycopyrrolate Moderate
- Bethanechol + Glycopyrrolate Moderate
- Chlorpromazine + Glycopyrrolate Moderate
- Clomipramine + Glycopyrrolate Moderate
- Clozapine + Glycopyrrolate Moderate
- Cyclizine + Glycopyrrolate Moderate
- Cyclobenzaprine + Glycopyrrolate Moderate
- Darifenacin + Glycopyrrolate Moderate
Pro+ 會員專屬
解鎖完整頁面
建立帳號並開始 Pro+ 試用，即可開啟 Glycopyrrolate 的完整藥品專論：劑量、懷孕與哺乳、副作用、警示及所有交互作用。
- Dosing by age, kidney and liver function, and further dose lines
- Renal and hepatic dose adjustments
- Paediatric dosing
- How to give it
- Pharmacokinetics
- Patient counselling points
- Food interactions
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同類別的其他藥品
常見問題
What is Glycopyrrolate used for?
Glycopyrrolate is a medicine in the class respiratory.
What side effects have been reported with Glycopyrrolate?
Dry mouth, Vomiting, Constipation, Flushing, Nasal congestion, Urinary retention.
Can Glycopyrrolate be taken in pregnancy or while breastfeeding?
Pregnancy: Unknown. Injection: very little crosses the placenta; widely used in anaesthesia, including caesarean section, without fetal heart effects. Oral and inhaled forms: no human data; no birth defects in rats or rabbits. Some UK injection labels: not recommended. Use only if clearly needed. Breastfeeding: Safe. No milk data; it is poorly absorbed by the infant (quaternary drug). Single doses (e.g. anaesthesia) and inhaled or skin use are unlikely to matter. Long-term oral use may reduce milk supply; watch the infant's weight gain.
What does Glycopyrrolate interact with?
MediHelp lists 80 known interactions for Glycopyrrolate. Major: 1 · Moderate: 48 · Minor: 31. The most serious include Potassium chloride, Amitriptyline, Atropine.
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