藥品參考
Glycopyrronium
Glycopyrronium is a medicine in the class respiratory. It is used for copd.
- 藥物類別: Respiratory
- 用途: copd
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本頁的臨床內容僅提供英文版。
重點資訊
- 藥物類別
- Respiratory
- ATC 代碼
- R03BB06, A03AB02
- 常見劑型
- 吸入器, 注射劑
- 常見規格
- 50 mcg, 1 mg/5 ml, 2.4 g/100 g
- 已知交互作用
- 107 (嚴重: 1 · 中度: 88 · 輕微: 18)
- 商品名
- 10
- 國家與市場
- 5
用途
作用方式
Long-acting muscarinic antagonist (LAMA); often referred to as an anticholinergic; produces bronchodilation by inhibiting acetylcholine’s effect on muscarinic receptors in the airway smooth muscle.
成人常用劑量(仿單摘要)
Surgery (Preoperative): 4mcg/kg IM 30-60 min before surgery. (Intraoperative): 0.1 mg IV; may repeat q2-3min
懷孕與哺乳
- 懷孕
- Unknown Injection: very little crosses the placenta; widely used in anaesthesia, including caesarean section, without fetal heart effects. Oral and inhaled forms: no human data; no birth defects in rats or rabbits. Some UK injection labels: not recommended. Use only if clearly needed.
- 哺乳
- Safe No milk data; it is poorly absorbed by the infant (quaternary drug). Single doses (e.g. anaesthesia) and inhaled or skin use are unlikely to matter. Long-term oral use may reduce milk supply; watch the infant's weight gain.
已通報的副作用
- Upper respiratory tract infection
- Nasopharyngitis
- Oropharyngeal pain
禁忌症
- Hypersensitivity to drug or components
- Glaucoma
- Obstructive uropathies, including prostatic hypertrophyMechanical obstructive diseases of gastrointestinal tract (eg, pyloroduodenalstenosis, strictures)
重要交互作用 (107)
- Clozapine + Glycopyrronium Major
- Abobotulinumtoxina + Glycopyrronium Moderate
- Aclidinium + Glycopyrronium Moderate
- Amantadine + Glycopyrronium Moderate
- Amitriptyline + Glycopyrronium Moderate
- Amoxapine + Glycopyrronium Moderate
- Atropine + Glycopyrronium Moderate
- Atropine iv / + Glycopyrronium Moderate
- Belladonna alkaloids + Glycopyrronium Moderate
- Belladonna and opium + Glycopyrronium Moderate
同類別的其他藥品
常見問題
What is Glycopyrronium used for?
Glycopyrronium is a medicine in the class respiratory. It is used for COPD.
What side effects have been reported with Glycopyrronium?
Upper respiratory tract infection, Nasopharyngitis, Oropharyngeal pain.
Can Glycopyrronium be taken in pregnancy or while breastfeeding?
Pregnancy: Unknown. Injection: very little crosses the placenta; widely used in anaesthesia, including caesarean section, without fetal heart effects. Oral and inhaled forms: no human data; no birth defects in rats or rabbits. Some UK injection labels: not recommended. Use only if clearly needed. Breastfeeding: Safe. No milk data; it is poorly absorbed by the infant (quaternary drug). Single doses (e.g. anaesthesia) and inhaled or skin use are unlikely to matter. Long-term oral use may reduce milk supply; watch the infant's weight gain.
What does Glycopyrronium interact with?
MediHelp lists 107 known interactions for Glycopyrronium. Major: 1 · Moderate: 88 · Minor: 18. The most serious include Clozapine, Abobotulinumtoxina, Aclidinium.
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