藥物交互作用
Acetylsalicylic acid + Lornoxicam
嚴重程度: 嚴重
Acetylsalicylic acid and Lornoxicam: major interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Taking aspirin with lornoxicam increases the risk of gastrointestinal ulceration and bleeding beyond that of either drug alone. The NSAID may also interfere with aspirin's antiplatelet effect.
用白話說明這項交互作用的意義
Acetylsalicylic acid and Lornoxicam can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Acetylsalicylic acid belongs to Musculoskeletal; Lornoxicam belongs to Musculoskeletal.
為什麼會發生
Additive inhibition of COX-1 reduces gastroprotective prostaglandins and platelet function, causing additive mucosal injury and bleeding tendency.
處置方式
Avoid the combination where possible; if both are needed, add a proton pump inhibitor and monitor for GI bleeding and anemia.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Acetylsalicylic acid 的其他交互作用
Lornoxicam 的其他交互作用
常見問題
Can I take Acetylsalicylic acid with Lornoxicam?
MediHelp rates the interaction as major. Acetylsalicylic acid and Lornoxicam can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Taking aspirin with lornoxicam increases the risk of gastrointestinal ulceration and bleeding beyond that of either drug alone. The NSAID may also interfere with aspirin's antiplatelet effect.
How serious is the interaction between Acetylsalicylic acid and Lornoxicam?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination where possible; if both are needed, add a proton pump inhibitor and monitor for GI bleeding and anemia.
What other medicines interact with Acetylsalicylic acid?
MediHelp also lists interactions of Acetylsalicylic acid with, for example, Ketorolac, Ketorolac intranasal, Abciximab. The full list is on the Acetylsalicylic acid page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
