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藥物交互作用

Ketorolac + Lornoxicam

嚴重程度: 禁忌併用

Ketorolac and Lornoxicam: contraindicated interaction.

最後更新

僅供醫療專業人員參考。本頁為簡要摘要,並非醫療建議,亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。

本頁的臨床內容僅提供英文版。

摘要

Taking ketorolac with lornoxicam raises the risk of gastrointestinal ulceration and bleeding, renal injury and cardiovascular events without better analgesia. Ketorolac is contraindicated with other NSAIDs.

用白話說明這項交互作用的意義

Ketorolac and Lornoxicam are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

Ketorolac belongs to Musculoskeletal; Lornoxicam belongs to Musculoskeletal.

證據等級: High

為什麼會發生

Additive cyclooxygenase inhibition affecting gastric mucosa, platelets and renal prostaglandins.

處置方式

Do not combine; use a single NSAID at the lowest effective dose.

可向藥師詢問的問題

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

Pro+ 會員專屬

解鎖完整頁面

建立帳號並開始 Pro+ 試用,即可解鎖 Ketorolac 與 Lornoxicam 的完整臨床處置建議、補充說明、證據詳情及整張處方的交互作用檢查工具。

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

在網頁版免費試用 Pro+ 14 天,無需信用卡。

常見問題

Can I take Ketorolac with Lornoxicam?

MediHelp rates the interaction as contraindicated. Ketorolac and Lornoxicam are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Taking ketorolac with lornoxicam raises the risk of gastrointestinal ulceration and bleeding, renal injury and cardiovascular events without better analgesia. Ketorolac is contraindicated with other NSAIDs.

How serious is the interaction between Ketorolac and Lornoxicam?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not combine; use a single NSAID at the lowest effective dose.

What other medicines interact with Ketorolac?

MediHelp also lists interactions of Ketorolac with, for example, Aceclofenac, Acemetacin, Acetylsalicylic acid. The full list is on the Ketorolac page.

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