藥物交互作用
Adalimumab + Rozanolixizumab
嚴重程度: 中度
Adalimumab and Rozanolixizumab: moderate interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Rozanolixizumab blocks the neonatal Fc receptor, which normally recycles IgG and protects it from degradation. Adalimumab is an IgG1 antibody, so its serum levels and effect may fall.
用白話說明這項交互作用的意義
Adalimumab and Rozanolixizumab can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Adalimumab belongs to Musculoskeletal; Rozanolixizumab belongs to Miscellaneous.
為什麼會發生
FcRn blockade by rozanolixizumab increases catabolism of IgG-based drugs such as adalimumab.
處置方式
Monitor for loss of adalimumab response, such as disease flare. If long-term adalimumab is essential, consider an alternative to rozanolixizumab.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Adalimumab 的其他交互作用
- Adalimumab + Bcg vaccine live 禁忌併用
- Adalimumab + Influenza virus vaccine quadrivalent intranasal 禁忌併用
- Adalimumab + Measles mumps and rubella vaccine 禁忌併用
- Adalimumab + Measles mumps and rubella vaccine live 禁忌併用
- Adalimumab + Measles mumps rubella and varicella vaccine live 禁忌併用
- Adalimumab + Measles vaccine 禁忌併用
Rozanolixizumab 的其他交互作用
常見問題
Can I take Adalimumab with Rozanolixizumab?
MediHelp rates the interaction as moderate. Adalimumab and Rozanolixizumab can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Rozanolixizumab blocks the neonatal Fc receptor, which normally recycles IgG and protects it from degradation. Adalimumab is an IgG1 antibody, so its serum levels and effect may fall.
How serious is the interaction between Adalimumab and Rozanolixizumab?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for loss of adalimumab response, such as disease flare. If long-term adalimumab is essential, consider an alternative to rozanolixizumab.
What other medicines interact with Adalimumab?
MediHelp also lists interactions of Adalimumab with, for example, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal, Measles mumps and rubella vaccine. The full list is on the Adalimumab page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
