藥物交互作用
Bevacizumab + Rozanolixizumab
嚴重程度: 中度
Bevacizumab and Rozanolixizumab: moderate interaction.
最後更新
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摘要
Rozanolixizumab blocks the neonatal Fc receptor and lowers circulating IgG, so it may shorten the half-life of IgG antibodies like bevacizumab and reduce their effect.
用白話說明這項交互作用的意義
Bevacizumab and Rozanolixizumab can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Bevacizumab belongs to Oncology; Rozanolixizumab belongs to Miscellaneous.
為什麼會發生
FcRn blockade reduces IgG recycling and increases catabolism of IgG monoclonal antibodies.
處置方式
Monitor for reduced bevacizumab efficacy; if prolonged bevacizumab therapy is essential, consider alternatives.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Bevacizumab 的其他交互作用
Rozanolixizumab 的其他交互作用
常見問題
Can I take Bevacizumab with Rozanolixizumab?
MediHelp rates the interaction as moderate. Bevacizumab and Rozanolixizumab can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Rozanolixizumab blocks the neonatal Fc receptor and lowers circulating IgG, so it may shorten the half-life of IgG antibodies like bevacizumab and reduce their effect.
How serious is the interaction between Bevacizumab and Rozanolixizumab?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for reduced bevacizumab efficacy; if prolonged bevacizumab therapy is essential, consider alternatives.
What other medicines interact with Bevacizumab?
MediHelp also lists interactions of Bevacizumab with, for example, Sunitinib, Daunorubicin, Dengue vaccine. The full list is on the Bevacizumab page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
