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藥物交互作用

Basiliximab + Rozanolixizumab

嚴重程度: 中度

Basiliximab and Rozanolixizumab: moderate interaction.

最後更新

僅供醫療專業人員參考。本頁為簡要摘要,並非醫療建議,亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。

本頁的臨床內容僅提供英文版。

摘要

Rozanolixizumab blocks the neonatal Fc receptor and increases IgG clearance, which could reduce basiliximab exposure and weaken IL-2 receptor blockade.

用白話說明這項交互作用的意義

Basiliximab and Rozanolixizumab can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Basiliximab belongs to Miscellaneous; Rozanolixizumab belongs to Miscellaneous.

證據等級: Low

為什麼會發生

FcRn blockade reduces IgG recycling and accelerates clearance of IgG monoclonal antibodies.

處置方式

Avoid giving rozanolixizumab around basiliximab dosing when possible and monitor for graft rejection or loss of effect.

可向藥師詢問的問題

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

Pro+ 會員專屬

解鎖完整頁面

建立帳號並開始 Pro+ 試用,即可解鎖 Basiliximab 與 Rozanolixizumab 的完整臨床處置建議、補充說明、證據詳情及整張處方的交互作用檢查工具。

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

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常見問題

Can I take Basiliximab with Rozanolixizumab?

MediHelp rates the interaction as moderate. Basiliximab and Rozanolixizumab can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Rozanolixizumab blocks the neonatal Fc receptor and increases IgG clearance, which could reduce basiliximab exposure and weaken IL-2 receptor blockade.

How serious is the interaction between Basiliximab and Rozanolixizumab?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid giving rozanolixizumab around basiliximab dosing when possible and monitor for graft rejection or loss of effect.

What other medicines interact with Basiliximab?

MediHelp also lists interactions of Basiliximab with, for example, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal, Measles mumps and rubella vaccine. The full list is on the Basiliximab page.

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