藥品參考
Rozanolixizumab
Rozanolixizumab is a medicine in the class miscellaneous. It is used for myasthenia gravis.
- 藥物類別: Miscellaneous
- 用途: myasthenia gravis
最後更新 來源: US FDA label
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
重點資訊
- 藥物類別
- Miscellaneous
- ATC 代碼
- L04AL02
- 常見劑型
- 注射劑
- 常見規格
- 140 mg/ml
- 已知交互作用
- 26 (嚴重: 1 · 中度: 25)
- 商品名
- 2
- 國家與市場
- 2
用途
作用方式
Humanized IgG4 monoclonal antibody that binds the neonatal Fc receptor (FcRn), reducing circulating IgG.
成人常用劑量（仿單摘要）
Generalized myasthenia gravis, body weight less than 50 kg: 420 mg (3 mL), subcutaneous infusion, once weekly for 6 weeks
懷孕與哺乳
- 懷孕
- Unknown Limited human data. US label: in monkeys it caused embryo death, low offspring weight and weak immune function at 10 to 30 times the human dose without maternal toxicity; the EU label reads the same studies as low IgG only. It lowers IgG passed to the baby; weigh live vaccines for the infant.
- 哺乳
- Unknown No human milk data; IgG passes into milk. US label: weigh benefits. EU label: a risk cannot be excluded in the first days after birth; afterwards consider use only if the benefit outweighs the risk. No LactMed record. A large antibody, so infant absorption is likely low.
已通報的副作用
- Headache
- Infections
- Diarrhea
- Pyrexia
- Hypersensitivity reactions
- Nausea
哪些人需要特別留意
- Infections: may increase infection risk; delay in active infection, monitor, and consider withholding for serious infection.
- Live or live-attenuated vaccines are not recommended during treatment because of reduced IgG.
- Aseptic meningitis: serious cases reported; start diagnostic workup and treatment if symptoms develop.
請告知藥師或醫師您是否懷孕或哺乳、是否患有腎臟或肝臟疾病、是否有過敏，以及您正在使用的所有其他藥物或保健品。
重要交互作用 (26)
- Rozanolixizumab + Upadacitinib Major
- Abatacept + Rozanolixizumab Moderate
- Adalimumab + Rozanolixizumab Moderate
- Ado-trastuzumab + Rozanolixizumab Moderate
- Basiliximab + Rozanolixizumab Moderate
- Bevacizumab + Rozanolixizumab Moderate
- Denosumab + Rozanolixizumab Moderate
- Etanercept + Rozanolixizumab Moderate
- Galcanezumab + Rozanolixizumab Moderate
- Golimumab + Rozanolixizumab Moderate
Pro+ 會員專屬
解鎖完整頁面
建立帳號並開始 Pro+ 試用，即可開啟 Rozanolixizumab 的完整藥品專論：劑量、懷孕與哺乳、副作用、警示及所有交互作用。
- Dosing by age, kidney and liver function, and further dose lines
- Renal and hepatic dose adjustments
- How to give it
- Pharmacokinetics
- Patient counselling points
- IV preparation and dilution
在網頁版免費試用 Pro+ 14 天，無需信用卡。
同類別的其他藥品
常見問題
What is Rozanolixizumab used for?
Rozanolixizumab is a medicine in the class miscellaneous. It is used for Myasthenia gravis.
What side effects have been reported with Rozanolixizumab?
Headache, Infections, Diarrhea, Pyrexia, Hypersensitivity reactions, Nausea.
Can Rozanolixizumab be taken in pregnancy or while breastfeeding?
Pregnancy: Unknown. Limited human data. US label: in monkeys it caused embryo death, low offspring weight and weak immune function at 10 to 30 times the human dose without maternal toxicity; the EU label reads the same studies as low IgG only. It lowers IgG passed to the baby; weigh live vaccines for the infant. Breastfeeding: Unknown. No human milk data; IgG passes into milk. US label: weigh benefits. EU label: a risk cannot be excluded in the first days after birth; afterwards consider use only if the benefit outweighs the risk. No LactMed record. A large antibody, so infant absorption is likely low.
What does Rozanolixizumab interact with?
MediHelp lists 26 known interactions for Rozanolixizumab. Major: 1 · Moderate: 25. The most serious include Upadacitinib, Abatacept, Adalimumab.
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在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
