藥物交互作用
Amiodarone + Valoctocogene roxaparvovec
嚴重程度: 中度
Amiodarone and Valoctocogene roxaparvovec: moderate interaction.
最後更新
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摘要
Amiodarone is hepatotoxic and valoctocogene roxaparvovec commonly causes transaminase elevation. Together they may increase liver injury and could reduce the benefit of gene therapy.
用白話說明這項交互作用的意義
Amiodarone and Valoctocogene roxaparvovec can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Amiodarone belongs to Cardiovascular; Valoctocogene roxaparvovec belongs to Miscellaneous.
為什麼會發生
Additive hepatotoxicity.
處置方式
Monitor ALT and other liver tests regularly after infusion. Consider an alternative antiarrhythmic if liver enzymes rise.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Amiodarone 的其他交互作用
Valoctocogene roxaparvovec 的其他交互作用
常見問題
Can I take Amiodarone with Valoctocogene roxaparvovec?
MediHelp rates the interaction as moderate. Amiodarone and Valoctocogene roxaparvovec can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Amiodarone is hepatotoxic and valoctocogene roxaparvovec commonly causes transaminase elevation. Together they may increase liver injury and could reduce the benefit of gene therapy.
How serious is the interaction between Amiodarone and Valoctocogene roxaparvovec?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ALT and other liver tests regularly after infusion. Consider an alternative antiarrhythmic if liver enzymes rise.
What other medicines interact with Amiodarone?
MediHelp also lists interactions of Amiodarone with, for example, Amisulpride, Arsenic trioxide, Dofetilide. The full list is on the Amiodarone page.
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