藥物交互作用
Amitriptyline + Azelastine
嚴重程度: 中度
Amitriptyline and Azelastine: moderate interaction.
最後更新
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摘要
Both drugs have sedative properties, and amitriptyline also has strong anticholinergic effects. Concurrent use may increase drowsiness, dizziness and impaired psychomotor performance.
用白話說明這項交互作用的意義
Amitriptyline and Azelastine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Amitriptyline belongs to Central Nervous System; Azelastine belongs to Respiratory.
為什麼會發生
Additive CNS depression via H1-receptor antagonism from both agents, plus anticholinergic effects of amitriptyline.
處置方式
Counsel on additive sedation and avoid driving until tolerance is established. Monitor elderly patients for confusion and falls.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Azelastine 的其他交互作用
Amitriptyline 的其他交互作用
常見問題
Can I take Amitriptyline with Azelastine?
MediHelp rates the interaction as moderate. Amitriptyline and Azelastine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs have sedative properties, and amitriptyline also has strong anticholinergic effects. Concurrent use may increase drowsiness, dizziness and impaired psychomotor performance.
How serious is the interaction between Amitriptyline and Azelastine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel on additive sedation and avoid driving until tolerance is established. Monitor elderly patients for confusion and falls.
What other medicines interact with Azelastine?
MediHelp also lists interactions of Azelastine with, for example, Calcium / magnesium / potassium / sodium oxybates, Methadone, Sodium oxybate. The full list is on the Azelastine page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
