藥物交互作用
Amlodipine-olmesartan + Carbidopa
嚴重程度: 中度
Amlodipine-olmesartan and Carbidopa: moderate interaction.
最後更新
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摘要
Carbidopa is used with levodopa, and the levodopa combination can cause orthostatic hypotension. This may add to the effect of antihypertensives. Carbidopa alone has little direct blood pressure effect.
用白話說明這項交互作用的意義
Amlodipine-olmesartan and Carbidopa can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Amlodipine-olmesartan belongs to Cardiovascular; Carbidopa belongs to Central Nervous System.
為什麼會發生
Additive hypotensive effect from levodopa-derived dopamine, enhanced by decarboxylase inhibition, together with antihypertensive vasodilation and RAS blockade.
處置方式
Monitor standing and sitting blood pressure when starting or titrating levodopa-carbidopa and reduce antihypertensive dosing if orthostatic symptoms occur.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Amlodipine-olmesartan 的其他交互作用
Carbidopa 的其他交互作用
常見問題
Can I take Amlodipine-olmesartan with Carbidopa?
MediHelp rates the interaction as moderate. Amlodipine-olmesartan and Carbidopa can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Carbidopa is used with levodopa, and the levodopa combination can cause orthostatic hypotension. This may add to the effect of antihypertensives. Carbidopa alone has little direct blood pressure effect.
How serious is the interaction between Amlodipine-olmesartan and Carbidopa?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor standing and sitting blood pressure when starting or titrating levodopa-carbidopa and reduce antihypertensive dosing if orthostatic symptoms occur.
What other medicines interact with Amlodipine-olmesartan?
MediHelp also lists interactions of Amlodipine-olmesartan with, for example, Aliskiren, Sparsentan, Amifostine. The full list is on the Amlodipine-olmesartan page.
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