藥物交互作用
Amlodipine-hydrochlorothiazide-valsartan + Carbidopa
嚴重程度: 中度
Amlodipine-hydrochlorothiazide-valsartan and Carbidopa: moderate interaction.
最後更新
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摘要
Carbidopa, usually given with levodopa, can add to blood pressure lowering and cause orthostatic hypotension in patients on antihypertensives. The effect is mostly due to levodopa.
用白話說明這項交互作用的意義
Amlodipine-hydrochlorothiazide-valsartan and Carbidopa can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Amlodipine-hydrochlorothiazide-valsartan belongs to Cardiovascular; Carbidopa belongs to Central Nervous System.
為什麼會發生
Levodopa-derived dopamine has additive vasodilatory and sympatholytic effects with antihypertensives.
處置方式
Monitor standing and sitting blood pressure when starting or increasing levodopa-carbidopa. Reduce antihypertensive doses if symptomatic hypotension occurs.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Amlodipine-hydrochlorothiazide-valsartan 的其他交互作用
- Aliskiren + Amlodipine-hydrochlorothiazide-valsartan 禁忌併用
- Amlodipine-hydrochlorothiazide-valsartan + Dofetilide 禁忌併用
- Amlodipine-hydrochlorothiazide-valsartan + Sparsentan 禁忌併用
- Aceclofenac + Amlodipine-hydrochlorothiazide-valsartan 嚴重
- Aldesleukin + Amlodipine-hydrochlorothiazide-valsartan 嚴重
- Amifostine + Amlodipine-hydrochlorothiazide-valsartan 嚴重
Carbidopa 的其他交互作用
常見問題
Can I take Amlodipine-hydrochlorothiazide-valsartan with Carbidopa?
MediHelp rates the interaction as moderate. Amlodipine-hydrochlorothiazide-valsartan and Carbidopa can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Carbidopa, usually given with levodopa, can add to blood pressure lowering and cause orthostatic hypotension in patients on antihypertensives. The effect is mostly due to levodopa.
How serious is the interaction between Amlodipine-hydrochlorothiazide-valsartan and Carbidopa?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor standing and sitting blood pressure when starting or increasing levodopa-carbidopa. Reduce antihypertensive doses if symptomatic hypotension occurs.
What other medicines interact with Amlodipine-hydrochlorothiazide-valsartan?
MediHelp also lists interactions of Amlodipine-hydrochlorothiazide-valsartan with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Amlodipine-hydrochlorothiazide-valsartan page.
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