藥物交互作用
Amlodipine-olmesartan-hydrochlorothiazide + Carbidopa
嚴重程度: 中度
Amlodipine-olmesartan-hydrochlorothiazide and Carbidopa: moderate interaction.
最後更新
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摘要
Carbidopa given with levodopa can cause orthostatic hypotension, which may be additive with antihypertensives. The effect is mainly seen when levodopa therapy is started or increased.
用白話說明這項交互作用的意義
Amlodipine-olmesartan-hydrochlorothiazide and Carbidopa can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Amlodipine-olmesartan-hydrochlorothiazide belongs to Cardiovascular; Carbidopa belongs to Central Nervous System.
為什麼會發生
Additive hypotensive effects from levodopa-derived dopamine and antihypertensive vasodilation and diuresis.
處置方式
Monitor sitting and standing blood pressure when starting or titrating levodopa/carbidopa and reduce antihypertensive doses if symptomatic hypotension occurs.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Amlodipine-olmesartan-hydrochlorothiazide 的其他交互作用
- Aliskiren + Amlodipine-olmesartan-hydrochlorothiazide 禁忌併用
- Amlodipine-olmesartan-hydrochlorothiazide + Dofetilide 禁忌併用
- Amlodipine-olmesartan-hydrochlorothiazide + Sparsentan 禁忌併用
- Acemetacin + Amlodipine-olmesartan-hydrochlorothiazide 嚴重
- Aldesleukin + Amlodipine-olmesartan-hydrochlorothiazide 嚴重
- Amifostine + Amlodipine-olmesartan-hydrochlorothiazide 嚴重
Carbidopa 的其他交互作用
常見問題
Can I take Amlodipine-olmesartan-hydrochlorothiazide with Carbidopa?
MediHelp rates the interaction as moderate. Amlodipine-olmesartan-hydrochlorothiazide and Carbidopa can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Carbidopa given with levodopa can cause orthostatic hypotension, which may be additive with antihypertensives. The effect is mainly seen when levodopa therapy is started or increased.
How serious is the interaction between Amlodipine-olmesartan-hydrochlorothiazide and Carbidopa?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor sitting and standing blood pressure when starting or titrating levodopa/carbidopa and reduce antihypertensive doses if symptomatic hypotension occurs.
What other medicines interact with Amlodipine-olmesartan-hydrochlorothiazide?
MediHelp also lists interactions of Amlodipine-olmesartan-hydrochlorothiazide with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Amlodipine-olmesartan-hydrochlorothiazide page.
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