藥物交互作用
Ampicillin + Omadacycline
嚴重程度: 中度
Ampicillin and Omadacycline: moderate interaction.
最後更新
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摘要
Bacteriostatic tetracyclines may blunt the killing activity of beta-lactams, which depend on actively dividing bacteria. The clinical importance is uncertain and mostly derived from in vitro and older clinical data. It may matter in serious infections such as meningitis or endocarditis.
用白話說明這項交互作用的意義
Ampicillin and Omadacycline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Ampicillin belongs to Anti Bacterial; Omadacycline belongs to Anti Bacterial.
為什麼會發生
Bacteriostatic inhibition of protein synthesis slows bacterial growth, reducing the bactericidal effect of cell-wall-active beta-lactams.
處置方式
Avoid the combination in severe infections where bactericidal activity is needed. If combined, monitor clinical response and consider using one agent alone.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Ampicillin 的其他交互作用
Omadacycline 的其他交互作用
常見問題
Can I take Ampicillin with Omadacycline?
MediHelp rates the interaction as moderate. Ampicillin and Omadacycline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Bacteriostatic tetracyclines may blunt the killing activity of beta-lactams, which depend on actively dividing bacteria. The clinical importance is uncertain and mostly derived from in vitro and older clinical data. It may matter in serious infections such as meningitis or endocarditis.
How serious is the interaction between Ampicillin and Omadacycline?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination in severe infections where bactericidal activity is needed. If combined, monitor clinical response and consider using one agent alone.
What other medicines interact with Ampicillin?
MediHelp also lists interactions of Ampicillin with, for example, Allopurinol, Bcg vaccine live, Chloramphenicol. The full list is on the Ampicillin page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
